New & Improved Combustion by BPS:
An Innovative & Extreme Fat Burning Formula!
NEW Combustion by BPS is a new and exciting fat burning/fat prevention formula!. It works to increase lipolysis and adrenergic stimulation, all while working to prevent redeposition of fat (fat gain) in the body.
Combustion will decrease appetite, improve mood, burn fat, and allow for rapid body recomposition.
Morus Alba (20:1 Extract)
Sourced from a specific mulberry tree native to China, Morus Alba is an exciting ingredient backed by quite a bit of research elucidating several potential benefits.
We'll start with direct implications on fat loss. MA has been shown to lower blood glucose, while reducing oxidative stress in the liver (1). Decreasing glucose encourages the body to be in a better metabolic position to access stored fat as a fuel source. It has since been shown in multiple studies to have a direct effect on fat loss by upregulating beta oxidation, by increasing expression of PPARa and COMT1, while simultaneously decreasing expression of Fatty Acid Synthase (FAS) (2–5). In simple terms, this means an increase in fat burning with a concurrent decrease in fat storage.
Recently, researchers discovered that MA had the ability of preventing pre-adipocytes from becoming mature fat cells (6). Intrigued by these results, those same researchers performed a follow up study to see how that actually played out as far as fat loss. What they found, was that when two groups were overfed, the group treated with MA gained 27% less weight, 15% less visceral (deep) fat, and the existing visceral fat cells reduced in size by almost 50% (7). It also appears that MA helps regulate adipokine functioning, preventing dysregulation that can potentially lead to increased fat gain due to excessive signaling of the fat storage cytokines, so basically "cleaning house" in the fat cells (8).
In addition to the fat loss benefits, MA has quite a bit of supportive data backing it as an effective regulator of blood lipids. It has been shown to be anti-hyperlipidemic, enhance the function of the LDL receptors (decreased function tends to upregulate LDL cholesterol production), increase the blood clearance of LDL cholesterol, and decrease actual production of LDL (9). Far more important than lowering LDL-C (which is nice, but doesn't necessarily reduce risk for heart disease), MA has been shown to lower LDL oxidation and foam cell formation (10). Foam cells are the immune derived cells that come in help and "patch things up" and swallow up oxidized LDL cholesterol at the damaged sites of fatty buildup in the arterial wall. Foam cells are more of a marker for arterial damage than they are the cause of damage, but they also can be dangerous themselves when they accumulate at one site. Another similar study noted that MA was able to significantly reduce susceptibility to LDL oxidation as well as decrease atherosclerotic lesion area (think of a wound in the arterial wall), by over 50% (11)
Alstonia scholaris is a specific tree from the Apocynaceae family, native to Southern parts of Asia. Several studies have demonstrated potential mechanisms of AS to aid in fat loss, as well as improve general health, and even boost performance.
AS has been identified as a b2 adrenergic receptor agonist, acting on the same fat cell receptor as clenbuterol to aid in fat loss (12). This also gives it bronchodilatory, anti-asthmatic and anti-tussive properties (13). Multiple other studies have confirmed this b2-AR mediated effect while also favorably modulating nitric oxide an prostaglandins, making it a solid choice for potential fat loss and performance enhancement (14,15).
A recent study found that AS acted as an adaptogen, aiding in the body's return to equilibrium from stress by regulating various catecholamines and neurotransmitters. The researchers even referred to it as having nootropic properties due to its ability to improve memory during stress. It also demonstrated free radical savaging abilities and helped to normalize stress induced cholesterol elevations (16).
In addition to confirming its antioxidant status, a 2012 review supported the use of AS for blood sugar/insulin reduction as an anti-diabetic agent, which has been used for this purpose in traditional medicine in certain communities for decades (14). Again, better blood sugar management sets the stage for better access to stored body fat. Aside from the b2-agonism, free radical scavenging, lipid regulation, cognitive enhancement and blood sugar management, a recent review of Alstonia also noted anti-anxiety, anti-inflammatory, hepatoprotective, anti-diabetic and analgesic properties (17). It would appear that Alstonia has quite a bit up its sleeve.
Also known as norcoclaurine, Higenamine is a major active component from aconite root, but can be found in at least seven different plants. Initial research on Higenamine was promising as it appeared to have similar effects to everybody's favorite fat burner ephedrine, but not until recently (literally just a few months ago as of the time of this publication) did we have legitimate human data. Previous data earned it a classification as a beta2-AR agonist (like the asthma drug and popular fat burner clenbuterol), which awarded it some attention from physique athletes in the past few years (18). Now we have some interesting real world data showing that a higenamine based combination product increased blood free fatty acids (FFA's) as well as energy expenditure after an overnight fast, versus the placebo group (19). It is important to remember that increasing blood FFA's is only the first step in fat burning (lipolysis), but the study did also note an actual increase in calories burned. Also recognize that this study was done with a combination product where the other ingredients (caffeine and yohimbine) more than likely contributed to the effect. However, caffeine is included in Combustion and we feel the other ingredients in our formula can more than match the effect of yohimbine without the possible undesirable elevation in heart rate and blood pressure common to many users.
It's no secret that forskolin has been widely recognized in the research as an effective lipolytic for over 30 years. Although we will not be taking an exhaustive appraisal of the research, as far back as 1987, we have data showing forskolin to be effective at reducing subcutaneous fat when applied transdermally (20). One of the main mechanisms of action is through activating adenylate cyclase which upregulates cyclic AMP production in fat cells, although other mechanisms are thought to exist (21,22).
So what does that actually mean for fat loss? One unpublished study out of Japan in 2001 showed a modest decrease in body fat in the subjects taking a forskolin product, which, while interesting, probably didn't serve much purpose other than to spawn further research due to several uncontrolled variables. Another study in 2005 showed that 12 weeksk of forskolin supplementation favorably altered body composition while boosting free testosterone and bone density in males (23). And a brand new (Feb. 2014) study attempted to fatten up rats and track the effects of various compounds on weight gain. The researchers found that forskolin was indeed able to prevent weight gain compared to controls (24).
While the research on b-PEA has traditionally focused on neurochemistry, it does possess some potentially potent benefits as a fat loss aid while concurrently improving mood. Through elevation of catecholamines like epinephrine and norepinephrine, b-PEA can contribute to activating beta adrenergic receptors in fat cells to kick start lipolysis while increasing expression of HSL (25). b-PEA anecdotally tends to act as an appetite suppressant in most users, making it easier to stick to a hypocaloric eating plan, which has been verified in rats (26). It is also widely recognized to improve mood even at low doses, however the effect is short lived without the presence of a MAO-b inhibitor. Combustion does include piperine, a nonselective MAOI, which while not nearly as potent as a prescription selective MAO-b inhibitor, will help to keep the mood enhancing effect of b-PEA active longer, coupled with the recommended protocol of taking three doses per day (27).
Caffeine is one of the most thoroughly researched compounds available for fat loss and performance enhancement. Here's some bullet points to summarize the immense data (28–36):
Increased cellular oxygen uptake during exercise.
Allows ability to perform more exercise with no increased sensation of effort
Moderate doses improve performance just as much as high doses
Blunts perceived exertion and pain perception, provides a more positive subjective experience while training .
Shown to be ergogenic in intense exercise ranging from 4-180 seconds, and improves performance in single and multiple sprint intervals .
Redosing caffeine six hours later not necessary to maintain increased performance in two-a-day workouts .
Significantly improves time to exhaustion during exercise, even when taken four hours prior to workout .
Retention of muscle while hypocaloric
Increased fat oxidation
You'll see piperine included in many ergogenic supplements these days, mainly to enhance the absorption and concentration in the bloodstream of other nutrients, which it does a great job of assuming the nutrient in question is broken down by a particular class of liver enzymes .
We've included piperine for this purpose, but also it's potential effects to increase fat loss and blood lipids on its own, according to recent research. While most of the current research has been using animal studies, the results are compelling.
In two recent studies, when attempting to fatten up mice, researchers found that piperine was able to improve insulin sensitivity and favorably modulate AMPK and adiponectin (37,38). Another very recent study overfed rats a bunch of carbs and fat for 16 weeks, and found that piperine was able to prevent damage over the control group to just about everything you can imagine; blood pressure, inflammation, oxidative stress, liver enzymes, and heart function (39). Multiple other studies have shown improvements in general health parameters like oxidative stress and dyslipidemia during overfeeding when compared to non-piperine controls (40,41). Another study using carbohydrate and fat overfeeding showed that piperine was able to significantly decrease body weight and visceral fat compared to controls (42).
As well, Piperine has been included in the formula for its Monoamine-Oxidase inhibitory properties. Monoamine Oxidade (also known as MAO) is an enzyme responsible for the rapid breakdown of biactive amines (dopamine, etc) and Catecholamines. It is also the enzyme responsible for the breakdown of b-PEA. Inhibition of this enzyme allows for the b-PEA to remain active for longer periods of time.
To assess tolerance, start by taking 1 capsule before breakfast and 1 capsule six to eight hours later.
This product is only intended to be consumed by healthy adults 18 years of age or older. Pregnant or nursing women should not use this product. Consult with your health care provider before using this product, especially if you are taking any prescription, over-the-counter medication, dietary supplement product or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAO-B inhibitor or any other medication, including but not limited to MAOIs, SSRIs, or any other compounds with serotonergic activity. This product contains caffeine and should not be taken by individuals wishing to eliminate this ingredient from their diet. Discontinue use 2 weeks prior to surgery. Do not use in combination with other caffeinated products. Discontinue use and immediately consult your health care professional if you experience any adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing. KEEP OUT OF REACH OF CHILDREN.
Take 1 serving in the morning and 1 serving before bed.
Not for use by individuals under the age of 18 years. Do not use if pregnant or nursing. Do not use if you have had a myocardio infarction (heart attack). You should not take this product if you have any prior medical condition, including diabetes or high blood pressure, or if you are taking any over-the-counter or prescription drugs. Consult your doctor before using this product. Keep out of reach of children and animals. Store in a dry and cool place.
Adaptogenic Stress Recovery Formula!
Modern lifestyle realities often take a huge toll on our general health. A constant demanding cycle of sleep deficit, stimulant use (whether coffee or energy drinks), stress, overwork, etc ends up sapping our energy and sabotaging productivity and mood.
While much of the popular supplementation promises revolve around a highly speculative condition of "adrenal fatigue", which has been conceptually abandoned by legitimate professionals who work closely with those displaying signs of adrenal dysfunction, a combination of factors does seem to manifest together.
So where does that leave us for supplementation, and what is the point of AdrenoSurge? AdrenoSurge has been designed to support optimal adrenal activity for those displaying mild to moderate signs of dysfunction, acting primarily as an adaptogen.
Some level of dysfunction is highly common in people with elevated stress levels, those that engage in vigorous exercise, regularly use stimulants, or do not get optimal duration and/or quality of sleep. Since a lot of people reading this fall into more than one of those categories, we feel that AdrenoSurge could help a high percentage of the health conscious population repair and recuperate from the daily damage done to the body; which will improve mental function, recovery from hard training, energy, stimulant sensitivity, and even body composition.
Destructive Consequences of Modern lifestyle:
Waking up tired
Energy crash at a consistent, specific time during the day
Energy surge during a consistent, specific time during the day (or night)
Trouble falling asleep or staying asleep
High blood sugar
Frequent brain fog
Lightheadedness when standing
Loss of sensitivity to stimulants
Sensitivity to light
Asparagus Racemosus Extract 100mg
Asparagus Racemosus is a particular species of asparagus used in Ayurvedic medicine for several purposes, including the alleviation of nervous disorders.
Working through optimization of GABA and serotonergic signaling, it has been shown in research to have similar anti-anxiety properties to Diazepam without the sedating characteristics (1,2). It has been shown to decrease elevated plasma levels of corticosterone and norepinephrine, acting as an adaptogen to favorably modulate stress pathways (3). When rats were exposed to chemical and physical stressors, pre-treatment with AR prevented elevation in blood glucose (a common secondary effect of high cortisol), triglycerides and lipid peroxidation. Researchers labeled it as having anti-stress properties (4,5). Rats have also demonstrated better memory retrieval, and better performance during stressful maze tests (6). In addition, AR has been shown to be an antioxidant, hepatoprotective, and neuroprotective (6–8).
Argyreia speciosa Extract 100mg
A popular Ayurvedic Indian medicinal plant, Argyreia Speciosa (AS) has been studied for it's potential combatance against a long list of maladies; including decreased cognitive function, low sex drive, depressed immunity, depressed CNS function, liver damage, elevated ROS, inflammation, high blood sugar, diarrhea, pain, and GI distress.
For our purposes, we will only be addressing a few specific potential benefits of AS supplementation. Similar to Asparagus Racemosus, AS has been shown to target and ameliorate several downstream effects of pathological stress including increased blood glucose, triglycerides, changes to the actual adrenal glands, as well as cortisol directly (9).
Another study demonstrated the ability of AS to restore adrenal levels of cortisol and ascorbic acid levels after chronic, non-specific stress (10). AS has also been shown to be a liver protectant on par with Silymarin, analgesic, anti-inflammatory, gastroprotective, and has even been shown to prevent fat gain in overfed rats (11–14).
Bacopa monnieri 20:1 100mg
Bacopa monnieri (BM) has been extensively studied for its positive mental benefits; a recent 2014 meta-analysis suggested its consistent ability to improve cognitive ability, which tends to decline as a downstream result of the effects of stress (15). Under stressful, adverse conditions, BM has been shown to favorably modulate CYP450, SOD, and Heat Shock Proteins (an intracellular clean up crew) (16).
Another 2014 study showed that in human subjects, during a stressful task, BM was able to exert positive effects on mood, a reduction in cortisol levels, and adaptogenic and nootropic effects (17).
Rhodiola rosea (8% Rosavins)
Rhodiola rosea (RR) is another well-studied herb with numerous potential benefits, with a recent meta-analysis concluding that it is able to improve both mental and physical performance during times of stress (18). It has been shown to prevent stress induced catecholamine release, which tends to be overactive in people with dysfunctional adrenals (19).
In one study with over 100 participants, RR was shown to improve life-stress symptoms to a clinically relevant degree after only 3 days of supplementation, and the positive effects lasted until cessation of data collection at 4 weeks (20). It has also been shown to help subjects resist fatigue, increase the ability to concentrate, and decrease cortisol response to awakening stress in fatigued patients (21). Other studies have classified RR as having anti-anxiety, anti-depressant, and physical and cognitive impairment reduction attributes (22,23).
Most products currently on the market are content with using anywhere between 1% and 3% Rosavins, while at the same time limiting dosage. AdrenoSurge is debuting a potent 8% Rosavin Rhodiola Rosea extract at a full 100mg dosage to maximize stress amelioration.
Ashwagandha 20:1 100mg
Ashwagandha is also considered an adaptogen, meaning it can help to dampen elevated cortisol, or help to boost low cortisol output, depending on what the body needs.
Multiple studies in human subjects have demonstrated Ashwagandha's ability to help the body cope with the downstream effects of stress. In one such study lasting 60 days, ashwagandha was shown to improve resistance towards stress and improve self-reported quality of life (24). A similar study found that chronic stress caused high blood sugar, glucose intolerance, increased plasma corticosterone levels, cognitive deficits, immunosuppression, and depression, whereas ashwagandha was able to have significant anti-stress activity on these parameters (25). It has also been shown to be a GABA mimetic anxiolytic, anti-inflammatory, and improve energy and mitochondrial health (26).
Bovine Adrenal Extract 10:1 125mg
While the basis for this extract is largely based on volumes of feedback from functional medicine practitioners versus published data, most users tend to notice a "boost" even when taken as a single ingredient product. Users with suboptimal cortisol output will notice the greatest benefit; particularly those that have lose sensitivity to stimulants. According to adrenal dysfunction expert Dr. Michael Lam, "Many report a sense of increased energy when previously fatigued and a sense of calmness when previously anxious after taking glandular extracts".
Evolvulus alsinoside (EA) is another potent adaptogen with several benefits (27). It has been shown to improve learning and memory in response to stress several recent studies (6,28,29). EA also demonstrates a nootropic effect that appears to be further enhanced when combined with Bacopa (30).
EA appears to alleviate several downstream effects of stress aside from learning impairment, such as oxidative load, anxiety, and CNS depression (29,31). And like Argyreia and Ashwagandha, EA is also able to normalize high blood sugar and elevated plasma corticosterone levels (32,33).
In summary, AdrenoSurge offers a multi-angle approach to help encourage optimal adrenal function while ameliorating potential negative downstream effects of the body's stress response. Coupled with appropriate lifestyle adjustments like reducing stimulant and alcohol intake and normalizing sleep patterns, AdrenoSurge should be a potent weapon in anyone's toolbox looking to optimize long term health, energy levels, cognitive function, and performance.
When you find that you no longer get the same effect from your preworkout or morning coffee, let AdrenoSurge restore you.
1. Garabadu D, Krishnamurthy S. Asparagus racemosus Attenuates Anxiety-Like Behavior in Experimental Animal Models. Cell Mol Neurobiol [Internet]. 2014 May [cited 2014 Apr 6];34(4):511–21. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24557501
2. Singh GK, Garabadu D, Muruganandam A V, Joshi VK, Krishnamurthy S. Antidepressant activity of Asparagus racemosus in rodent models. Pharmacol Biochem Behav [Internet]. 2009 Jan [cited 2014 Apr 6];91(3):283–90. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18692086
3. Krishnamurthy S, Garabadu D, Reddy NR. Asparagus racemosus modulates the hypothalamic-pituitary-adrenal axis and brain monoaminergic systems in rats. Nutr Neurosci [Internet]. 2013 Nov [cited 2014 Apr 6];16(6):255–61. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23485433
4. Joshi T, Sah SP, Singh A. Antistress activity of ethanolic extract of Asparagus racemosus Willd roots in mice. Indian J Exp Biol [Internet]. 2012 Jun [cited 2014 Apr 6];50(6):419–24. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22734253
5. Hannan JMA, Ali L, Khaleque J, Akhter M, Flatt PR, Abdel-Wahab YHA. Antihyperglycaemic activity of Asparagus racemosus roots is partly mediated by inhibition of carbohydrate digestion and absorption, and enhancement of cellular insulin action. Br J Nutr [Internet]. 2012 May [cited 2014 Apr 6];107(9):1316–23. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21899804
6. Shah J, Goyal R. Investigation of neuropsychopharmacological effects of a polyherbal formulation on the learning and memory process in rats. J Young Pharm [Internet]. 2011 Apr [cited 2013 Aug 28];3(2):119–24. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3122040&tool=pmcentrez&rendertype=abstract
7. Sharma K, Bhatnagar M, Kulkarni SK. Effect of Convolvulus pluricaulis Choisy and Asparagus racemosus Willd on learning and memory in young and old mice: a comparative evaluation. Indian J Exp Biol [Internet]. 2010 May [cited 2014 Apr 6];48(5):479–85. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20795365
8. Visavadiya NP, Soni B, Madamwar D. Suppression of reactive oxygen species and nitric oxide by Asparagus racemosus root extract using in vitro studies. Cell Mol Biol (Noisy-le-grand) [Internet]. 2009 Jan [cited 2014 Apr 6];55 Suppl:OL1083–95. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19267991
9. Patel NB, Galani VJ, Patel BG. Antistress activity of Argyreia speciosa roots in experimental animals. J Ayurveda Integr Med [Internet]. 2011 Jul [cited 2014 Apr 7];2(3):129–36. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3193684&tool=pmcentrez&rendertype=abstract
10. Habbu P V, Mahadevan KM, Kulkarni P V, Daulatsingh C, Veerapur VP, Shastry RA. Adaptogenic and in vitro antioxidant activity of flavanoids and other fractions of Argyreia speciosa (Burm.f) Boj. in acute and chronic stress paradigms in rodents. Indian J Exp Biol [Internet]. 2010 Jan [cited 2014 Apr 7];48(1):53–60. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20358867
11. Habbu P V, Shastry RA, Mahadevan KM, Joshi H, Das SK. Hepatoprotective and antioxidant effects of Argyreia speciosa in rats. Afr J Tradit Complement Altern Med [Internet]. 2008 Jan [cited 2014 Apr 7];5(2):158–64. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2816541&tool=pmcentrez&rendertype=abstract
12. Bachhav RS, Gulecha VS, Upasani CD. Analgesic and anti-inflammatory activity of Argyreia speciosa root. Indian J Pharmacol [Internet]. 2009 Aug [cited 2014 Apr 7];41(4):158–61. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2875733&tool=pmcentrez&rendertype=abstract
13. Jaiswal SK, Rao C V, Sharma B, Mishra P, Das S, Dubey MK. Gastroprotective effect of standardized leaf extract from Argyreia speciosa on experimental gastric ulcers in rats. J Ethnopharmacol [Internet]. 2011 Sep 1 [cited 2014 Apr 7];137(1):341–4. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21658440
14. Kumar S, Alagawadi KR, Rao MR. Effect of Argyreia speciosa root extract on cafeteria diet-induced obesity in rats. Indian J Pharmacol [Internet]. 2011 Apr [cited 2014 Apr 7];43(2):163–7. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3081454&tool=pmcentrez&rendertype=abstract
15. Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, Limpeanchob N, Norman Scholfield C. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol [Internet]. 2014 Jan 10 [cited 2014 Apr 1];151(1):528–35. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24252493
16. Chowdhuri DK, Parmar D, Kakkar P, Shukla R, Seth PK, Srimal RC. Antistress effects of bacosides of Bacopa monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain. Phytother Res [Internet]. 2002 Nov [cited 2014 Apr 7];16(7):639–45. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12410544
17. Benson S, Downey LA, Stough C, Wetherell M, Zangara A, Scholey A. An Acute, Double-Blind, Placebo-Controlled Cross-over Study of 320 mg and 640 mg Doses of Bacopa monnieri (CDRI 08) on Multitasking Stress Reactivity and Mood. Phytother Res [Internet]. 2014 Apr [cited 2014 Apr 7];28(4):551–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23788517
18. Hung SK, Perry R, Ernst E. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials. Phytomedicine [Internet]. 2011 Feb 15 [cited 2013 Sep 21];18(4):235–44. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21036578
19. Maslova L V, Kondrat’ev BI, Maslov LN, Lishmanov IB. [The cardioprotective and antiadrenergic activity of an extract of Rhodiola rosea in stress]. Eksp Klin Farmakol [Internet]. [cited 2014 Apr 7];57(6):61–3. Available from: http://www.ncbi.nlm.nih.gov/pubmed/7756969
20. Edwards D, Heufelder A, Zimmermann A. Therapeutic effects and safety of Rhodiola rosea extract WS® 1375 in subjects with life-stress symptoms--results of an open-label study. Phytother Res [Internet]. 2012 Aug [cited 2013 Oct 7];26(8):1220–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22228617
21. Olsson EM, von Schéele B, Panossian AG. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med [Internet]. 2009 Feb [cited 2014 Apr 2];75(2):105–12. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19016404
22. Perfumi M, Mattioli L. Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. extract in mice. Phytother Res [Internet]. 2007 Jan [cited 2014 Apr 7];21(1):37–43. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17072830
23. Huang S-C, Lee F-T, Kuo T-Y, Yang J-H, Chien C-T. Attenuation of long-term Rhodiola rosea supplementation on exhaustive swimming-evoked oxidative stress in the rat. Chin J Physiol [Internet]. 2009 Oct;52(5):316–24. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20034236
24. Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med [Internet]. 2012 Jul [cited 2013 Sep 3];34(3):255–62. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3573577&tool=pmcentrez&rendertype=abstract
25. Bhattacharya SK, Muruganandam A V. Adaptogenic activity of Withania somnifera: an experimental study using a rat model of chronic stress. Pharmacol Biochem Behav [Internet]. 2003 Jun [cited 2014 Apr 7];75(3):547–55. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12895672
26. Singh N, Bhalla M, de Jager P, Gilca M. An overview on ashwagandha: a Rasayana (rejuvenator) of Ayurveda. Afr J Tradit Complement Altern Med [Internet]. 2011 Jan [cited 2013 Sep 20];8(5 Suppl):208–13. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3252722&tool=pmcentrez&rendertype=abstract
27. Siripurapu KB, Gupta P, Bhatia G, Maurya R, Nath C, Palit G. Adaptogenic and anti-amnesic properties of Evolvulus alsinoides in rodents. Pharmacol Biochem Behav [Internet]. 2005 Jul [cited 2014 Apr 7];81(3):424–32. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15899513
28. Nahata A, Patil UK, Dixit VK. Effect of Evolvulus alsinoides Linn. on learning behavior and memory enhancement activity in rodents. Phytother Res [Internet]. 2010 Apr [cited 2014 Apr 7];24(4):486–93. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19610035
29. Malik J, Karan M, Vasisht K. Nootropic, anxiolytic and CNS-depressant studies on different plant sources of shankhpushpi. Pharm Biol [Internet]. 2011 Dec [cited 2014 Apr 7];49(12):1234–42. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21846173
30. Gupta A, Raj H, Karchuli MS, Upmanyu N. Comparative evaluation of ethanolic extracts of Bacopa monnieri, Evolvulus alsinoides, Tinospora cordifolia and their combinations on cognitive functions in rats. Curr Aging Sci [Internet]. 2013 Dec [cited 2014 Apr 7];6(3):239–43. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23866011
31. Kumar M, Ahmad A, Rawat P, Khan MF, Rasheed N, Gupta P, et al. Antioxidant flavonoid glycosides from Evolvulus alsinoides. Fitoterapia [Internet]. 2010 Jun [cited 2014 Apr 7];81(4):234–42. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19748554
32. Gupta P, Sharma U, Gupta P, Siripurapu KB, Maurya R. Evolvosides C–E, flavonol-4’-O-triglycosides from evolvulus alsinoides and their anti-stress activity [corrected]. Bioorg Med Chem [Internet]. 2013 Mar 1 [cited 2014 Apr 7];21(5):1116–22. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23357036
33. Gupta P, Akanksha, Siripurapu KB, Ahmad A, Palit G, Arora A, et al. Anti-stress constituents of Evolvulus alsinoides: an ayurvedic crude drug. Chem Pharm Bull (Tokyo) [Internet]. 2007 May [cited 2014 Apr 7];55(5):771–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17473466
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease or illness.
FAT BURNER WITH CRAVE CONTROL
ALL DAY ENERGY, MOOD ELEVATION & FOCUS*
Suggested in research to decrease the drop-out rate of individuals on low calorie diet protocols*
Supports appetite control so caloric intake can be reduced*
Supports positive mood while dieting*
Powerful all day energy, mood support and focus*
Further enhance the fat burning process of exercise (via inhibiting alpha2 receptors)*
Great as a pre-workout energy/focus enhancer
PhosphoLean N-Oleoyl-PE + EGCG
PhosphoLean® N-Oleoyl-PE + EGCG (NOPE + EGCG) is the "next generation" nutritional supplement compound for advanced craving control and weight management.* PhosphoLean® NOPE + EGCG is a safe, natural, and effective nutritional supplement compound that can help individuals manage their ideal body weight.*
Recent research involving the appetite suggested that helping support a healthy appetite level may help reduce the intake of food, thus it’s an effective means for controlling both energy balance and body weight. Since appetite support and craving control are major controlling points for energy (food) intake, managing appetite is crucial in controlling healthy body weight, especially when combined with health conscious lifestyle choices that include attention to proper food intake, dietary supplementation, and exercise.
Under the severe stress levels experienced during dieting, studies suggest that PhosphoLean® NOPE + EGCG can effectively help individuals manage the daily stress of their calorie reduced diets and help them stay on diets for longer periods of time.* Only this will lead to long-term diet success.
Rauwolfia vomitoria (standardized
We have included the highest standardized extract for alpha-yohimbine currently available. Unlike typical yohimbe extracts or yohimbine HCL, which impact both alpha and beta-andrenergic receptors, alpha yohimbine used in LIV is much more specific and works predominantly as an alpha2 receptor antagonist.* The benefit of alpha-yohimbineʼs specificity as an antagonist to the alpha2 receptors are as follows:
Our bodies fat cells (specifically in the subcutaneous fat tissue) have a much higher number of alpha 2 receptors compared to beta receptors.
Alpha2 receptors when activated, blunt/decrease the fat burning process.
By blocking these alpha2 receptors with alpha-yohimbine, you may help your body to burn fat more effectively.* This receptor specificity, allows alpha-yohimbine to have a much stronger fat burning affect than common yohimbe extracts or yohimbine HCL. In addition, alpha-yohimbine exhibits far fewer negatives side effects often experienced with typical yohimbe.*
A developed specialized wild green oat extract, that concentrates specific constituents of the plant that have been suggested in research to boost the neurotransmitter dopamine and have a positive impact on stress resistance.* The overall benefit is greater alertness, energy and focus, while helping support a healthy stress response.* By including Neuravena, we further enhance the end users optimal mental state needed to assist them throughout their day as they progress through their chosen diet protocol.
Stimulates alpha wave activity in the brain and has been suggested when combined with caffeine to be highly beneficial in improving alertness during demanding tasks. As an additional benefit, Theanine has been suggested in research to accelerate mental regeneration after exercise and reduce the negative side effects of caffeine. The perfect supplement to combat diet and exercise induced neurological burnout that frequently occurs when dieting and training hard.
A key component factor of LIV's formula responsible for:
Supporting mental focus*
Sense of well being*
Vanillean is a revolutionary new thermogenic product from BPS. Vanillean is a powerful thermogenic that offers an innovative approach to fat burning! By targeting the activation of several thermoregulatory receptors, Vanillean causes a massive release of stored fatty acids from fat cells, forcing your body to then burn it ALL as heat and energy. Burning fat without the use of jittery stimulants, Vanillean supports rapid and the most effective approach to fat loss!
Vanillean manipulates the body’s thermoregulatory sensors to trick the body into thinking it requires dramatic energy expenditure in order to balance out the body’s temperature and maintain ideal conditions. Hot and cold at the same time, the body turns to its primary fuel source – body fat – to try to bring itself into balance.
This effect is all illusion, however. Using herbal and other extracts, we are able to trick the body into burning significant fat stores to both generate heat, and cool the body at the same time. Combined with a potent vasodilation activity, Vanillean results in rapid fat loss without the use of stimulants, and without uncomfortable side effects.